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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b27dd5d6e05efe8c560a0fdb46648aa1b597c0a4992be7d981a3f5005da253' 
  AND token = '60jmk87oxTnGbD4gNObT5gAM55jy+pE7rLXG2/+HSoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}