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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0add6e7ed40b60d4114e74f937134d1a9bc756c50d54703c5bdeaed6e1f4b569' 
  AND token = 'h9VAxX0iFTpz8eVRXOsr8L4zkkcQElnFDiVD9VC8NWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}