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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee04e49e7e9c55721bbc4a56ab3ca3f499b6cdac77c68243a4a56f777a4e2368' 
  AND token = 'QKd+QAz2fUPOP3cf9xgNxdS9iy1OH7hi5hXZ6ENVkR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}