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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c88d5f4ba905aacd5b9f388839dd47c1eb00d06ae5707079e4badf0a8b5cc8' 
  AND token = 'gC6bLMeMXRPnjd/bUqqbSmLJkn5MyCLn8UXbaKMlCy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}