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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '997c947c1cdd06c79bfda4b5a93c2ac87d4cbe81880d6c28c9f32db741e6b1b1' 
  AND token = 'XkMbL94NZanjSMAH+P/y3zheUZLbAi79ixdYLLwIhOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}