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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74207658453c6d868012070f50ace20728a1ef4bda03b40c1d1fe8a3fdcc5cf4' 
  AND token = 'vmch/u5tNr/JfQwMcqTv91+cmtgxxgIujeG+PlowZw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}