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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646d49dd30b1fad1c68daca7cb360d871ee0562dd8a73dc2cbf71c4cd074ff94' 
  AND token = '5auzZ6DJDLwooA/iGJNGL5fweQjfWK+f9HG8m/Rq36A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}