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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e126121d65d763e72838b64ac302e8671f49ff14b09e820efe70f5dee5380697' 
  AND token = 'OzDKIlmOY2OuFJxDJsa507zB9FJZGg+D0ITRs986mRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}