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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b10130c2f141f919ec07066c3a336086301d694f7e4ed9a9d81a8317474f1d' 
  AND token = '3TLC+LDQe9fHF6OylNUxtJVDCQOd9zTAQhuIQc1uzYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}