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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7e0d4ebde463afb0ee34dc4164e582274e9d3d67fe3f2d3cb19223fd299dccb' 
  AND token = 'IcNglx07CG2dO4a4SDaSLXmdBS1EkBQWNaI1mJrJpGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}