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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7fef8a97f378c9530bee8acbf8c0d2c94a5ab938e6dad121e808933e9f1b942' 
  AND token = 'NR+b3bapsSAmlDyeE5H+Up3rStQWQAkE6clEZfiP3uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}