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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53dceaea8776f87a430a4aefb0067c66d28eac027886dfedae84e09cee4eb5a1' 
  AND token = '/zOApCT7RmU/99vE1kkPiMD8Vn0xAHMzCwChKWILmlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}