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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b242212ead54ed4f0e851d0f46111cc24f55dbab4abf71aa661bedad62cbb079' 
  AND token = 'JCF0oakflDEBrUzsqG0NtnxFYf+O9Vbr07XJCD3Vo4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}