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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d00f10a50b51200737279390aaaf273ed5af9fb9d5e58caa9a8179b0f042fe8' 
  AND token = 'sPV96HkbqyLTIYsTIyG9h1KM1uIT7BIpVGFMNTrXjDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}