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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2d9b673e4dad8b1e08e454240d1c1a609a4563641ed5894a294fae655e56a5' 
  AND token = 'NoD/pddOuSU1zRK63U+c4Llym05b4hd4YjYsYgW/2Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}