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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '584e00ba3050554e4cb0ae137eea58d2b57831f8dd10bde391d6b489fd812851' 
  AND token = 'L6yVRe6V+iI7srUcOQqg/2WGv5CMRy6OfF7WsjJcfUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}