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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ebe11d0a79523a1924e80ef18a570393e4aa5d18c38b86feccb4a90f75e1a4' 
  AND token = 'x1TKmvrHXFghL0kfgIBPOAA+YjWU3jsUmARlm4hYX70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}