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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ac1f35cced6c97de4af860d5a47e5cf1e4983e0d57098bf4df1fdff3972316' 
  AND token = 'fUIXy6FSBHM8qiwbhN8pmMWa+c4WtXNewENbbJklxWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}