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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad814fa5ea059e1a129bb346dcc3224a57a90e47108ef82c3966839e0e817c8' 
  AND token = 'trhglEWzsEE7Aj/IQdgrg2GqQlekhCK43nz5GbALjNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}