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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100814521950a793b305d7ff0d85b144c2e225421ae29d6342448991d7e79336' 
  AND token = 'dqakPJaVtMTFDOmkyk8hbPxMojIBC+qJJX2v0N1CdnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}