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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f10e5ad1bf211a82aa4b48894ef983c8b801f0fdbe4a816488c6c50b6b3e1a' 
  AND token = 'tl5l9ySObzY8soFbdp3mhe+BjD52Alqv5DTkMq+hxl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}