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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24eb8a53fc45bb8399b3a37caf0e7698fb0b858994fbf882586f9e4a0bcc6488' 
  AND token = 'b9ZgK0CB8ZLvT+oSu8gJHEeetDUEE6I8v55MzcsM2Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}