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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '244cba5a6ee3831e0c2d61803e0fb47eaff99a4eae353df6d97d763b39e378d7' 
  AND token = 'SVgnilNMZVZkm6NGpspd5HDHhYkfBKGGZ9osK9iK4dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}