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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0628b0d70e4d3c62e60386b719502185c4642f094b6a2e5c7c04a212329f280' 
  AND token = 'l18W0RZ05RpunLkqe/Va4pwq/4hNeD+SS0rAR0V2O8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}