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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '415887a21f2419c8b95367ce955a0c0029927696f83de21f75949e82816681cb' 
  AND token = '0IvSoyJSI5w5ohQfTvU1mKYLZ6FPdQfPK/dx2IB9tps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}