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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '674de7c4f649bf9bf34e9e39e13686dc414322ab45130a56d0689db7c441236a' 
  AND token = 'BA/eDRdCVoM0RBns+62oDDAlpd1rPKEFmD7ctEKTBdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}