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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4dfed120cf82f5fbf119dc5b8cf5301f3e4ccf37c66cbf38bf9b581e9f37809' 
  AND token = 'D/X/JXdGA+Fjgcd/vg6v+AzNAJln4+Iu7SnBAk9Fd6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}