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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '783d0823acf58c2c27d30ca1a3fab7633081b69f9b360903d710749d69b4c6d1' 
  AND token = 'yegwm0fhd8fWkGmyaGWsr5Ym3qN4LpvhEf1ISA7Knc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}