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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3476ea6c0ffdb6b9b464876493f3a4487c5a9020f7eaf1b127a3fe9e05e1a7cf' 
  AND token = '+j5y9+JLbnTLr7NTEuR8uMTRdkTZ22McOTFHOhgaF8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}