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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2255d4e867f27db92aa5bc3bbbde57a0984dc950b4b4d086181bf62970b7314' 
  AND token = '+Pq6Ls5gge5kwSJ1PhLhDqLcz+6S4WJow5ipk3aRBMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}