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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea9190359d42ddbc7d7a0d01088e0a9b14db5739bdf7a898ef2cbcbf53f376be' 
  AND token = '189Z+EHSp72x482OUARiu4LCEqNNB6ahRR2LTefnoNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}