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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d5d3219e3f33c8cb84e8d64df85562ed7aef28196dd36ef32e9542c1113130' 
  AND token = 'XMxJ++5tkP8ayzQsfcDf0hezSVgKbD5/BOARTYglmV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}