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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be71a49fbf5424e1515146e501262d406c393136ebe2108d015c9b196c09ae32' 
  AND token = 'pzglF2rvk5stoFHFSuzIA35NL2obLDWSf59gBLO9dW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}