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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b40f16a4df72d3f48625891a5809ead07e195e647e020ba2cf8b1205c0e555c5' 
  AND token = 'Xb/bFmUFpOTTnkT4Lm0OYX5jfmT2PyxG83F+OYRkCXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}