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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a33f4b55b7c2c9dbf21ffadb49804b0b910ad7c8b32691edf93aa95594cc45' 
  AND token = 'EYUwfb7bmBe+1p6JXXivcouYNfKhEsIc5qMdNV3O90I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}