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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d85989b401d8d0f279337e6936f708126d01841a4e5aee1ae8c3ed0037d46f4' 
  AND token = 'rS9Rx4TonIRhcB1SXlq8jEyqQLEV9DarZODs5dwDmrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}