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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '583a127d2d8ba1c2e0a155e77a026e713592d0a17e9677bc865bdb4eed20f400' 
  AND token = 'LxqM4LaftCSe0hYoUYK/u5qRIkESNNyWEci0zglZG4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}