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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f7124787548b723b964edd6215d437d2d74c55cc5548074ed516b9e2dfc9446' 
  AND token = 'Dx777EtmF95wfQczYd3Om+sPvamf764u1399bkhBRHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}