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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2904ad456c524e8eb742512cc995a25e639a53f6f2a8d1305a0dd12eff9c28ca' 
  AND token = 'IE2YsDa/hR00ActOX3FeM9rBfyz7Vr9kD0Ghhe0IkKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}