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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09eef89a6b7991b5e1b6a76027a606ddbaa5978270b79e67066955c3f6a4c1c9' 
  AND token = 'oy/wt0VuEuuqm4lWzpfttbFoe7UjvX4gq9hGLiiaXIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}