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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6a5a5db0ed997904f2d9043a27f0a689e40df525629aa64c94675afa1491a0' 
  AND token = 'P4dtB8daVKbMVF6o+AWk7bo/ZGMQaM/1QDxshT0BYBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}