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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38f96c16f2602f2172d015c6be5d41ec9219a5b3eaefe774bb173a6bb9e185cf' 
  AND token = 'jXJjEu0HVXtxdhHnMFmzlPJ9Odb5kCwatsVpW1xp1p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}