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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406f9be71aeb7f60f1790b637e18b3d22e2e7aba387fce9a93a694fc8b801f72' 
  AND token = '3HE37tMOQaCAn7/e53dq0KROmyujgP5YKhePXiIuCJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}