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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cf95785b2fa60ac5960e03ef27f1767a0a8a45e0092027c0bcf9c488d351a33' 
  AND token = '0+GXyQwRa0I7phVg+PrQ1Ar7mCDQ8PQOylAdbWYFuaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}