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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a77bbe469b7f41cac2aa5c60cb4b8a50902ec8f3f5394ba150c31a5e6f2e43' 
  AND token = 'NHwgw3u/3RCLgCYmUFFHKjCrPtMbmzlLZiQEKw6P24M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}