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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eede6f648e3fb143effd35207bedbae8e291b7e799737337024e0f08a6420f5d' 
  AND token = 'rixXsi0tpn/KckkJVOc/AoB+2LRKZn2ZsmMj/r6Wsxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}