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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665f3345d5e6d32dffa87f4898a233c2b7f44a7aa29dc61049bb8b5cb4898cd2' 
  AND token = '+Y9GHdCyMdpG80UvEQE249yo3xaftHwPb2THUI6IZoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}