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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a42a9703529562febf64391147396799c728c953e64287ea9d6e67f939402a3' 
  AND token = 'rZIUgoNCoBPO8uSeWbbkn94mJ2FCLchBExo/hU1v0BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}