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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f63756d687c32c54a73cd927e239687149115431178d468d0ba552414bdda34' 
  AND token = 'YJTyO5LQ+z0LEmH9+Au2j+ADRb9OjRJwdtU+7WF9oRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}