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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e033a33f55f6dd5dc4140e6038254ac6cb7dca6c0b1a05024532ca4322e9665' 
  AND token = 'df9wGdjoYg4VHL/qqekEQ/nvXaFTZw2SNg0tp5V8eAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}